Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis

BACKGROUND: Macrophage apoptosis and MMP activity contribute to vulnerability of atherosclerotic plaques to rupture. By employing molecular imaging techniques, we investigated if apoptosis and MMP release are interlinked. METHODS: Atherosclerosis was produced in rabbits receiving high-cholesterol di...

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Detalhes bibliográficos
Main Authors: Haider, Nezam, Hartung, Dagmar, Fujimoto, Shinichiro, Petrov, Artiom, Kolodgie, Frank D., Virmani, Renu, Ohshima, Satoru, Liu, Han, Zhou, Jun, Fujimoto, Ai, Tahara, Atsuko, Hofstra, Leo, Narula, Navneet, Reutelingsperger, Chris, Narula, Jagat
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746297/
https://ncbi.nlm.nih.gov/pubmed/19662466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12350-009-9107-8
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