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Pathway Engineered Enzymatic de novo Purine Nucleotide Synthesis

A general method for isotopic labeling of the purine base moiety of nucleotides and RNA has been developed through biochemical pathway engineering in vitro. A synthetic scheme was designed and implemented utilizing recombinant enzymes from the pentose phosphate and de novo purine synthesis pathways,...

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Detalhes bibliográficos
Main Authors: Schultheisz, Heather L., Szymczyna, Blair R., Scott, Lincoln G., Williamson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746247/
https://ncbi.nlm.nih.gov/pubmed/18707057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800066p
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