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Normal RNAi response in human fragile × fibroblasts

BACKGROUND: Fragile × syndrome is caused by loss of expression of the FMRP protein involved in the control of a large number of mRNA targets. The Drosophila ortholog dFXR interacts with a protein complex that includes Argonaute2, an essential component of the RNA-induced silencing complex (RISC). Fu...

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Detalhes bibliográficos
Main Authors: Madsen, Charlotte, Grønskov, Karen, Brøndum-Nielsen, Karen, Jensen, Thomas G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746233/
https://ncbi.nlm.nih.gov/pubmed/19740428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-177
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