Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells

PTEN is a dual function phosphatase with tumor suppressor function compromised in a wide spectrum of cancers. Because tissue polarity and architecture are crucial modulators of normal and malignant behavior, we postulated that PTEN may play a role in maintenance of tissue integrity. We used two non-...

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Hauptverfasser: Fournier, Marcia V., Fata, Jimmie, Martin, Katherine, Yaswen, Paul, Bissell, Mina J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746025/
https://ncbi.nlm.nih.gov/pubmed/19417140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1694
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