A Candidate Precursor to Pelvic Serous Cancer (p53 Signature) and Its Prevalence in Ovaries and Fallopian Tubes from Women with Heterozygous BRCA Mutations

BACKGROUND: Early serous carcinomas (SCAs) predominate in the fimbria of BRCA+ women. An entity in non-neoplastic mucosa sharing several properties of SCA - the “p53 signature” - has been described in the distal fallopian tube and proposed as a precursor to SCA. This study compared the prevalence of...

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Main Authors: Folkins, Ann K., Jarboe, Elke A., Saleemuddin, Aasia, Lee, Yonghee, Callahan, Michael J., Drapkin, Ronny, Garber, Judy, Muto, Michael G., Tworoger, Shelley, Crum, Christopher P
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746001/
https://ncbi.nlm.nih.gov/pubmed/18342932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2008.01.012
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