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BMP2 Is Essential for Post Natal Osteogenesis but Not for Recruitment of Osteogenic Stem Cells

The effects of BMP2 on bone marrow stromal cell differentiation and bone formation after bone marrow ablation were determined using C57 BL/6J (B6) mice. Inhibition of BMP2 expression with lentiviral BMP2 shRNA prevented both mineralized nodule formation in vitro and bone formation in vivo, and block...

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Detalhes bibliográficos
Main Authors: Bais, MV, Wigner, N, Young, M, Toholka, R, Graves, DT, Morgan, EF, Gerstenfeld, LC, Einhorn, TA
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745982/
https://ncbi.nlm.nih.gov/pubmed/19398045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.04.239
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