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Hand2 is required in the epithelium for palatogenesis in mice
The basic helix-loop-helix (bHLH) transcription factor Hand2 has been implicated in the development of multiple organs, including craniofacial organs. Mice carrying Hand2 hypomorphic alleles (Hand2(LoxP/−)) display a cleft palate phenotype. A specific deletion of the Hand2 branchial arch-specific en...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745957/ https://ncbi.nlm.nih.gov/pubmed/19341725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.03.021 |
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