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Hand2 is required in the epithelium for palatogenesis in mice

The basic helix-loop-helix (bHLH) transcription factor Hand2 has been implicated in the development of multiple organs, including craniofacial organs. Mice carrying Hand2 hypomorphic alleles (Hand2(LoxP/−)) display a cleft palate phenotype. A specific deletion of the Hand2 branchial arch-specific en...

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Detalhes bibliográficos
Main Authors: Xiong, Wei, He, Fenglei, Morikawa, Yuka, Yu, Xueyan, Zhang, Zunyi, Lan, Yu, Jiang, Rulang, Cserjesi, Peter, Chen, YiPing
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745957/
https://ncbi.nlm.nih.gov/pubmed/19341725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.03.021
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