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Potent Induction of IFN-α and Chemokines by Autoantibodies in the Cerebrospinal Fluid of Patients with Neuropsychiatric Lupus

Neuropsychiatric disease in systemic lupus erythematosus (NPSLE) is a poorly understood, but potentially fatal, disease manifestation. A pathogenetic role for autoantibodies is suspected, but the mechanism is unclear. Since immune complexes in SLE can stimulate IFN-α and there is strong evidence in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Santer, Deanna M., Yoshio, Taku, Minota, Seiji, Möller, Thomas, Elkon, Keith B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745922/
https://ncbi.nlm.nih.gov/pubmed/19124763
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