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Serotonin 5-HT(2) Receptors Induce a Long-Lasting Facilitation of Spinal Reflexes Independent of Ionotropic Receptor Activity

Dorsal root-evoked stimulation of sensory afferents in the hemisected in vitro rat spinal cord produces reflex output, recorded on the ventral roots. Transient spinal 5-HT(2C) receptor activation induces a long-lasting facilitation of these reflexes (LLFR) by largely unknown mechanisms. Two Sprague-...

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Autori principali: Shay, Barbara L., Sawchuk, Michael, Machacek, David W., Hochman, Shawn
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745843/
https://ncbi.nlm.nih.gov/pubmed/16033939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00465.2005
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