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From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways

BACKGROUND: Single nucleotide polymorphisms (SNPs) are the most frequent type of sequence variation between individuals, and represent a promising tool for finding genetic determinants of complex diseases and understanding the differences in drug response. In this regard, it is of particular interes...

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Detalhes bibliográficos
Main Authors: Bauer-Mehren, Anna, Furlong, Laura I, Rautschka, Michael, Sanz, Ferran
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745588/
https://ncbi.nlm.nih.gov/pubmed/19758470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-S8-S6
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