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Multiple Domains of Endopin 2A for Serpin Cross-Class Inhibition of Papain
The serpin endopin 2A inhibits the cysteine protease papain in cross-class inhibition. This study demonstrates the novel finding that both the non-RSL NH(2)-domain and the RSL domain with P1-P1′ residues participate in endopin 2A inhibition. Production of a chimeric mutant of endopin 2A with replace...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745395/ https://ncbi.nlm.nih.gov/pubmed/17451636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.02.036 |
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