Genomewide Scan Reveals Association of Psoriasis with IL-23 and NF-κB Pathways

Psoriasis is a common immune mediated disorder that affects the skin, nails, and joints. To identify psoriasis susceptibility loci, we genotyped 438,670 SNPs in 1,409 European ancestry psoriasis cases and 1,436 controls. Twenty-one promising SNPs were followed-up in 5,048 psoriasis cases and 5,041 c...

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Detalhes bibliográficos
Main Authors: Nair, Rajan P., Duffin, Kristina Callis, Helms, Cindy, Ding, Jun, Stuart, Philip E., Goldgar, David, Gudjonsson, Johann E., Li, Yun, Tejasvi, Trilokraj, Feng, Bing Jian, Ruether, Andreas, Schreiber, Stefan, Weichenthal, Michael, Gladman, Dafna, Rahman, Proton, Schrodi, Steven J., Prahalad, Sampath, Guthery, Stephen L, Fischer, Judith, Liao, Wilson, Kwok, Pui-Yan, Menter, Alan, Lathrop, G. Mark, Wise, Carol A., Begovich, Ann B., Voorhees, John J., Elder, James T., Krueger, Gerald G., Bowcock, Anne M., Abecasis, Gonçalo R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745122/
https://ncbi.nlm.nih.gov/pubmed/19169254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.311
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