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Repetitive Immunization Enhances the Susceptibility of Mice to Peripherally Administered Prions

The susceptibility of humans and animals to prion infections is determined by the virulence of the infectious agent, by genetic modifiers, and by hitherto unknown host and environmental risk factors. While little is known about the latter two, the activation state of the immune system was surmised t...

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Detalhes bibliográficos
Main Authors: Bremer, Juliane, Heikenwalder, Mathias, Haybaeck, Johannes, Tiberi, Cinzia, Krautler, Nike Julia, Kurrer, Michael O., Aguzzi, Adriano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744926/
https://ncbi.nlm.nih.gov/pubmed/19779609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007160
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