EGFR, p16, HPV Titer, Bcl-xL and p53, Sex, and Smoking As Indicators of Response to Therapy and Survival in Oropharyngeal Cancer

PURPOSE: To prospectively identify markers of response to therapy and outcome in an organ-sparing trial for advanced oropharyngeal cancer. PATIENTS AND METHODS: Pretreatment biopsies were examined for expression of epidermal growth factor receptor (EGFR), p16, Bcl-xL, and p53 as well as for p53 muta...

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Main Authors: Kumar, Bhavna, Cordell, Kitrina G., Lee, Julia S., Worden, Francis P., Prince, Mark E., Tran, Huong H., Wolf, Gregory T., Urba, Susan G., Chepeha, Douglas B., Teknos, Theodoros N., Eisbruch, Avraham, Tsien, Christina I., Taylor, Jeremy M.G., D'Silva, Nisha J., Yang, Kun, Kurnit, David M., Bauer, Joshua A., Bradford, Carol R., Carey, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744895/
https://ncbi.nlm.nih.gov/pubmed/18474878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.12.7662
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