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Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells
The formation of adequate masses of endocrine and exocrine pancreatic tissues during embryogenesis is essential to ensure proper nutrition and glucose homeostasis at postnatal stages. We generated mice with pancreas-specific ablation of the 3-phosphoinositide–dependent protein kinase 1 (Pdk1) to inv...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744847/ https://ncbi.nlm.nih.gov/pubmed/19635472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.07.030 |
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