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Unraveling pathology in juvenile Alexander disease: serial quantitative MR imaging and spectroscopy of white matter

INTRODUCTION: Alexander disease is a rare disorder of the central nervous system with characteristic symmetric white matter abnormalities with frontal predominance on magnetic resonance (MR) images. Histopathology shows a lack of myelin in the affected white matter, variably interpreted as hypomyeli...

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Autors principals: van der Voorn, J. Patrick, Pouwels, Petra J. W., Salomons, Gajja S., Barkhof, Frederik, van der Knaap, Marjo S.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744817/
https://ncbi.nlm.nih.gov/pubmed/19484233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00234-009-0540-9
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