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BRCA1 Down-Regulates Cellular Levels of Reactive Oxygen Species

Previous studies have shown that the breast cancer suppressor BRCA1 stimulates antioxidant gene expression and protects cells against oxidative stress. To further examine this important function, we tested whether BRCA1 could modulate intracellular levels of reactive oxygen species (ROS). Wild-type...

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Main Authors: Saha, Tapas, Rih, Jeong Keun, Rosen, Eliot M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744635/
https://ncbi.nlm.nih.gov/pubmed/19364506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.04.005
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