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Inactivation of the Haemophilus ducreyi luxS Gene Affects the Virulence of this Pathogen in Human Subjects

Haemophilus ducreyi 35000HP contains a homolog of the luxS gene, which encodes an enzyme that synthesizes the AI-2 autoinducer in other gram-negative bacteria. H. ducreyi 35000HP produced AI-2 that functioned in a Vibrio harveyi-based reporter system. An H. ducreyi luxS mutant was constructed by ins...

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Autores principales: Labandeira-Rey, Maria, Janowicz, Diane M., Blick, Robert J., Fortney, Kate R., Zwickl, Beth, Katz, Barry P., Spinola, Stanley M., Hansen, Eric J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744376/
https://ncbi.nlm.nih.gov/pubmed/19552526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/600142
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