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Functional Role of the Carboxyl Terminal Domain of Human Connexin 50 in Gap Junctional Channels

Gap junction channels formed by connexin 50 (Cx50) are critical for maintenance of lens transparency. Because the C-terminus of Cx50 can be cleaved post-translationally, we hypothesized that channels formed by the truncated Cx50 exhibit altered properties or regulation. We used the dual whole-cell p...

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Autors principals: Xu, X., Berthoud, V.M., Beyer, E.C., Ebihara, L.
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744361/
https://ncbi.nlm.nih.gov/pubmed/11944087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-001-0139-5
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