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Using Dendritic Cell Maturation and IL-12 Producing Capacity as Markers of Function: A Cautionary Tale

Effective dendritic cell (DC) function depends on sufficient expression of antigen and costimulatory molecules, and secretion of interleukin (IL)-12. We sought to augment DC stimulatory capacity by optimizing DC phenotype and IL-12 production. DCs, obtained by CD14-selection, were matured using 8 di...

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Detalhes bibliográficos
Main Authors: Kaka, Anjum S., Foster, Aaron E., Weiss, Heidi L., Rooney, Cliona M., Leen, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744357/
https://ncbi.nlm.nih.gov/pubmed/18391760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318165f5d2
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