Toxicology and pharmacokinetics of 1-methyl-[D]-tryptophan: absence of toxicity due to saturating absorption

1-methyl-D-tryptophan (D-1MT) reverses the immunosuppressive effect of indoleamine 2,3-dioxygenase (IDO), and it is currently being developed both as a vaccine adjuvant and as an immunotherapeutic agent for combination with chemotherapy. The present study examined the pharmacokinetics and toxicity o...

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Bibliografiset tiedot
Päätekijät: Jia, Lee, Schweikart, Karen, Tomaszewski, Joseph, Page, John G., Noker, Patricia E., Buhrow, Sarah A., Reid, Joel M., Ames, Matthew M., Munn, David H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744343/
https://ncbi.nlm.nih.gov/pubmed/17868966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2007.07.017
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