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Subunit counting in membrane-bound proteins

The subunit number and stoichiometry of membrane-bound proteins are difficult to determine without disrupting their membrane environment. Here we describe a single-molecule technique for counting subunits of proteins in live cell membranes by observing bleaching steps of GFP fused to a protein of in...

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Autori principali: Ulbrich, Maximilian H, Isacoff, Ehud Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744285/
https://ncbi.nlm.nih.gov/pubmed/17369835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/NMETH1024
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