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Loss of Dendritic HCN1 Subunits Enhances Cortical Excitability and Epileptogenesis
Hyperpolarization-activated cation nonselective 1 (HCN1) plasticity in entorhinal cortical (EC) and hippocampal pyramidal cell dendrites is a salient feature of temporal lobe epilepsy. However, the significance remains undetermined. We demonstrate that adult HCN1 null mice are more susceptible to ka...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744118/ https://ncbi.nlm.nih.gov/pubmed/19726656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1531-09.2009 |
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