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Loss of Dendritic HCN1 Subunits Enhances Cortical Excitability and Epileptogenesis

Hyperpolarization-activated cation nonselective 1 (HCN1) plasticity in entorhinal cortical (EC) and hippocampal pyramidal cell dendrites is a salient feature of temporal lobe epilepsy. However, the significance remains undetermined. We demonstrate that adult HCN1 null mice are more susceptible to ka...

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Detalhes bibliográficos
Main Authors: Huang, Zhuo, Walker, Matthew C., Shah, Mala M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744118/
https://ncbi.nlm.nih.gov/pubmed/19726656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1531-09.2009
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