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Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors

Small molecules that reconstitute the binding mode(s) of a protein and in doing so elicit a programmed functional response offer considerable advantages in the control of complex biological processes. The development challenges of such molecules are significant, however. Many protein-protein interac...

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Detalhes bibliográficos
Main Authors: Buhrlage, Sara J., Bates, Caleb A., Rowe, Steven P., Minter, Aaron R., Brennan, Brian B., Majmudar, Chinmay Y., Wemmer, David E., Al-Hashimi, Hashim, Mapp, Anna K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744096/
https://ncbi.nlm.nih.gov/pubmed/19348463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900028j
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