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Cellular responses to dietary cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species

PURPOSE: Present study was undertaken to elucidate the mechanism of cellular responses to D,L-sulforaphane (SFN), a highly promising cancer chemopreventive agent. METHODS: Mitochondrial DNA deficient Rho-0 variants of LNCaP and PC-3 cells were generated by culture in the presence of ethidium bromide...

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Detalhes bibliográficos
Main Authors: Xiao, Dong, Powolny, Anna A., Antosiewicz, Jedrzej, Hahm, Eun-Ryeong, Bommareddy, Ajay, Zeng, Yan, Desai, Dhimant, Amin, Shantu, Herman-Antosiewicz, Anna, Singh, Shivendra V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744077/
https://ncbi.nlm.nih.gov/pubmed/19384467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-009-9883-5
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