Scleraxis Is Required for Cell Lineage Differentiation and Extracellular Matrix Remodeling During Murine Heart Valve Formation In Vivo

Heart valve structures, derived from mesenchyme precursor cells, are composed of differentiated cell types and extracellular matrix arranged to facilitate valve function. Scleraxis (scx) is a transcription factor required for tendon cell differentiation and matrix organization. This study identified...

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Hauptverfasser: Levay, Agata K., Peacock, Jacqueline D., Lu, Yinhui, Koch, Manuel, Hinton, Robert B., Kadler, Karl E., Lincoln, Joy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743952/
https://ncbi.nlm.nih.gov/pubmed/18802027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.177238
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