A large multicenter analysis of CTGF -945 promoter polymorphism does not confirm association with Systemic Sclerosis susceptibility or phenotype

OBJECTIVE: In this work we conducted a replication study to investigate whether the -945 CTGF genetic variant is associated with SSc susceptibility or specific SSc phenotype. METHODS: The study population comprised of 1180 SSc patients and 1784 healthy controls from seven independent case-control se...

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Main Authors: Rueda, B, Simeon, C, Hesselstrand, R, Herrick, A, Worthington, J, Ortego-Centeno, N, Riemekasten, G, Fonollosa, V, Vonk, MC, van den Hoogen, FHJ, Sanchez-Román, J, Aguirre-Zamorano, MA, García-Portales, R, Pros, A, Camps, MT, Gonzalez-Gay, MA, Gonzalez-Escribano, MF, Coenen, MJ, Lambert, N, Nelson, JL, Radstake, TRDJ, Martin, J.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743760/
https://ncbi.nlm.nih.gov/pubmed/19054816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2008.100180
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