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Tumor and host-mediated pathways of resistance and disease progression in response to antiangiogenic therapy

Despite early benefits seen in cancer patients treated with anti-VEGF pathway targeted drugs, the clinical benefits obtained in terms of progression-free or overall survival have been more modest than expected. This is, at least in part, due to antiangiogenic drug resistance mechanisms that involve...

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Autors principals: Ebos, John M.L., Lee, Christina R., Kerbel, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743513/
https://ncbi.nlm.nih.gov/pubmed/19671869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0095
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