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Repeated Cannabinoid Injections into the Rat Periaqueductal Gray Enhances Subsequent Morphine Antinociception

Cannabinoids and opiates inhibit pain, in part, by activating the periaqueductal gray (PAG). Evidence suggests this activation occurs through distinct mechanisms. If the antinociceptive mechanisms are distinct, then cross-tolerance between opioids and cannabinoids should not develop. This hypothesis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wilson, Adrianne R., Maher, Lauren, Morgan, Michael M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743428/
https://ncbi.nlm.nih.gov/pubmed/18723035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.07.038
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