Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane

BACKGROUND: Considerable interest lies in the identification of novel anti-angiogenic compounds for cancer therapy. We have investigated whether dexrazoxane has anti-angiogenic properties and if so, the mechanism of the inhibition. METHODS: The phenotypic effects of dexrazoxane on endothelial cell b...

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Главные авторы: Maloney, S L, Sullivan, D C, Suchting, S, Herbert, J M J, Rabai, E M, Nagy, Z, Barker, J, Sundar, S, Bicknell, R
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2009
Предметы:
Translational Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743367/
https://ncbi.nlm.nih.gov/pubmed/19738618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605203
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