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Reduced myocardial creatine kinase flux in human myocardial infarction: An in vivo phosphorus magnetic resonance spectroscopy study

BACKGROUND: Energy metabolism is essential for myocellular viability. The high-energy phosphates, ATP and phosphocreatine (PCr), are reduced in human myocardial infarction (MI), reflecting myocyte loss and/or decreased intracellular ATP generation by creatine kinase (CK), the heart's prime ener...

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Detalhes bibliográficos
Main Authors: Bottomley, Paul A., Wu, Katherine C., Gerstenblith, Gary, Schulman, Steven P., Steinberg, Angela, Weiss, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743337/
https://ncbi.nlm.nih.gov/pubmed/19332463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.823187
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