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Ah receptor represses acute phase response gene expression without binding to its cognate response element
Repression of the NF-κB pathway has been extensively researched due to its pivotal role in inflammation. We investigated the potential of the aryl hydrocarbon receptor (AHR) to suppress NF-κB regulated gene expression, especially acute phase genes, such as serum amyloid A (Saa). Using AHR mutants, i...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743259/ https://ncbi.nlm.nih.gov/pubmed/19333233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.24 |
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