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Identification by Automated Screening of a Small Molecule that Selectively Eliminates Neural Stem Cells Derived from hESCs but Not Dopamine Neurons

BACKGROUND: We have previously described fundamental differences in the biology of stem cells as compared to other dividing cell populations. We reasoned therefore that a differential screen using US Food and Drug Administration (FDA)-approved compounds may identify either selective survival factors...

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Main Authors: Han, Yi, Miller, Aaron, Mangada, Julie, Liu, Ying, Swistowski, Andrzej, Zhan, Ming, Rao, Mahendra S., Zeng, Xianmin
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743191/
https://ncbi.nlm.nih.gov/pubmed/19774075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007155
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