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Normal Dopaminergic Nigrostriatal Innervation in SPG3A Hereditary Spastic Paraplegia

SPG3A/atlastin-1 gene mutations cause an autosomal dominant form of hereditary spastic paraplegia (SPG3A-HSP). We used positron emission tomography with [(11)C]DTBZ to assess nigrostriatal dopaminergic integrity in two unrelated adults with SPG3A-HSP due to the common SPG3A/atlastin-1 mutation, R239...

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Détails bibliographiques
Auteurs principaux: Albin, Roger L., Koeppe, Robert A., Rainier, Shirley, Fink, John K.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743137/
https://ncbi.nlm.nih.gov/pubmed/19085270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01677060802337307
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