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Orexigenic Hormone Ghrelin Ameliorates Gut Barrier Dysfunction In Sepsis In Rats
OBJECTIVE: We have recently shown that ghrelin, a novel orexigenic hormone, is reduced in sepsis. Ghrelin treatment, mediated through ghrelin receptors in the brain, attenuates sepsis-induced inflammation and mortality. Gut barrier dysfunction is common in sepsis. High mobility group B1 (HMGB1) incr...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742951/ https://ncbi.nlm.nih.gov/pubmed/19531942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181a557a2 |
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