NaKtide, a Na/K-ATPase-derived Peptide Src Inhibitor, Antagonizes Ouabain-activated Signal Transduction in Cultured Cells

We have previously shown that the Na/K-ATPase binds and inhibits Src. Here, we report the molecular mechanism of Na/K-ATPase-mediated Src regulation and the generation of a novel peptide Src inhibitor that targets the Na/K-ATPase/Src receptor complex and antagonizes ouabain-induced protein kinase ca...

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Detalhes bibliográficos
Main Authors: Li, Zhichuan, Cai, Ting, Tian, Jiang, Xie, Joe X., Zhao, Xiaochen, Liu, Lijun, Shapiro, Joseph I., Xie, Zijian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742871/
https://ncbi.nlm.nih.gov/pubmed/19506077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.013821
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