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Intramolecular Isopeptide Bonds Give Thermodynamic and Proteolytic Stability to the Major Pilin Protein of Streptococcus pyogenes

The pili expressed by Streptococcus pyogenes and certain other Gram-positive bacterial pathogens are based on a polymeric backbone in which individual pilin subunits are joined end-to-end by covalent isopeptide bonds through the action of sortase enzymes. The crystal structure of the major pilin of...

詳細記述

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書誌詳細
主要な著者: Kang, Hae Joo, Baker, Edward N.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742838/
https://ncbi.nlm.nih.gov/pubmed/19497855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014514
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