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Actin-Mediated Endocytosis Limits Intracellular Cr Accumulation and Cr Toxicity during Chromate Stress

Chromate toxicity is well documented, but the underlying toxic mechanism(s) has yet to be fully elucidated. Following a Cr toxicity screen against > 6000 heterozygous yeast mutants, here we show that Cr resistance requires normal function of the cortical actin cytoskeleton. Furthermore, Cr-stress...

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Autori principali: Holland, Sara L., Avery, Simon V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742586/
https://ncbi.nlm.nih.gov/pubmed/19628586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp170
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