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Estrogen Carcinogenesis: Specific Identification of Estrogen-modified Nucleobase in Breast Tissue from Women
Prolonged exposure to estrogens correlates with increased risk for breast cancer. One explanation is that estrogen metabolites cause mutations by reacting with DNA, leading to depurination. We describe an extraction procedure and a liquid chromatographic tandem mass spectrometric (LC/MS/MS) assay to...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742319/ https://ncbi.nlm.nih.gov/pubmed/18672910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx8001737 |
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