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RP105 facilitates macrophage activation by mycobacterial lipoproteins and viable Mycobacterium tuberculosis
RP105, a Toll-like receptor (TLR)–like molecule, is reported to facilitate B cell activation by the TLR4-agonist LPS but to limit LPS-induced cytokine production by antigen-presenting cells. We show that RP105 positively regulates macrophage responses to Mycobacterium tuberculosis (Mtb). Mtb-infecte...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742161/ https://ncbi.nlm.nih.gov/pubmed/19154986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.12.002 |
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