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The Spinster homologue, Two of Hearts, is required for sphingosine 1-phosphate signaling in zebrafish

The bioactive lipid sphingosine 1-phosphate (S1P) and its G protein-coupled receptors play critical roles in cardiovascular, immune and neural development and function [1–6]. Despite its importance, many questions remain about S1P signaling, including how S1P, which is synthesized intracellularly, i...

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Hlavní autoři: Osborne, Nick, Brand-Arzamendi, Koroboshka, Ober, Elke A., Jin, Suk-Won, Verkade, Heather, Holtzman, Nathalia Glickman, Yelon, Deborah, Stainier, Didier Y.R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741689/
https://ncbi.nlm.nih.gov/pubmed/19062281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.10.061
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