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Potent Anti-Inflammatory and Neuroprotective Effects of TGFβ1 Are Mediated through the Inhibition of ERK and p47(phox)-Ser345 Phosphorylation and Translocation in Microglia

TGFβ1 is one of the most potent endogenous immune modulators of inflammation. The molecular mechanism of its anti-inflammatory effect on the activation of the transcription factor NF-kB has been well studied, however, the potential effects of TGFβ1 on other pro-inflammatory signaling pathways is les...

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Autors principals: Qian, Li, Wei, Sung-Jen, Zhang, Dan, Hu, Xiaoming, Xu, Zongli, Wilson, Belinda, El-Benna, Jamel, Hong, Jau-Shyong, Flood, Patrick M
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741684/
https://ncbi.nlm.nih.gov/pubmed/18566433
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