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Transcriptional Signature and Memory Retention of Human-Induced Pluripotent Stem Cells

Genetic reprogramming of somatic cells to a pluripotent state (induced pluripotent stem cells or iPSCs) by over-expression of specific genes has been accomplished using mouse and human cells. However, it is still unclear how similar human iPSCs are to human Embryonic Stem Cells (hESCs). Here, we des...

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Detalhes bibliográficos
Main Authors: Marchetto, Maria C. N., Yeo, Gene W., Kainohana, Osamu, Marsala, Martin, Gage, Fred H., Muotri, Alysson R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741600/
https://ncbi.nlm.nih.gov/pubmed/19763270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007076
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