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Comparison of Oxaliplatin- and Cisplatin-induced Painful Peripheral Neuropathy in the Rat

While platinum-based cancer chemotherapies produce painful peripheral neuropathy as dose-limiting side effects, there are important differences in the pain syndromes produced by members of this class of drugs. In the rat Cisplatin-induced hyperalgesia has latency to onset of 24–48 hrs, is maximal by...

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Bibliographic Details
Main Authors: Joseph, Elizabeth K., Levine, Jon D.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741410/
https://ncbi.nlm.nih.gov/pubmed/19231296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2008.12.003
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