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Orexin-1 receptor antagonism decreases ethanol consumption and preference selectively in high-ethanol-preferring Sprague Dawley rats

Work from our laboratory has shown that orexin (ORX; or hypocretin) neurons in the lateral hypothalamus are involved in preference for morphine, cocaine, and food. Other groups have demonstrated a connection between the ORX system and ethanol-related behaviors. Here we extended those results to inve...

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Detalhes bibliográficos
Main Authors: Moorman, David E., Aston-Jones, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741398/
https://ncbi.nlm.nih.gov/pubmed/19671464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2009.07.002
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