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CYP1B1 expression in ovarian cancer in the laying hen Gallus domesticus

OBJECTIVES: Ovarian carcinoma is the most lethal gynecological malignancy. The genetic and molecular mechanisms that cause it still remain largely unknown. CYP1B1 is a cytochrome P450 enzyme that catalyzes the conversion of estrogens to genotoxic catechol estrogens which may cause DNA mutations and...

詳細記述

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書誌詳細
主要な著者: Zhuge, Yan, Lagman, Jo Ann J., Ansenberger, Kristine, Mahon, Cassandra J., Daikoku, Takiko, Dey, Sudhansu K., Bahr, Janice M., Hales, Dale B.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741324/
https://ncbi.nlm.nih.gov/pubmed/18973935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2008.09.026
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