Neural Activity Changes Underlying the Working Memory Deficit in Alpha-CaMKII Heterozygous Knockout Mice

The alpha-isoform of calcium/calmodulin-dependent protein kinase II (α-CaMKII) is expressed abundantly in the forebrain and is considered to have an essential role in synaptic plasticity and cognitive function. Previously, we reported that mice heterozygous for a null mutation of α-CaMKII (α-CaMKII+...

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Main Authors: Matsuo, Naoki, Yamasaki, Nobuyuki, Ohira, Koji, Takao, Keizo, Toyama, Keiko, Eguchi, Megumi, Yamaguchi, Shun, Miyakawa, Tsuyoshi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2009
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741293/
https://ncbi.nlm.nih.gov/pubmed/19750198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/neuro.08.020.2009
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