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CRYPTIC PEPTIDES OF THE KRINGLE DOMAINS PREFERENTIALLY BIND TO DISEASE-ASSOCIATED PRION PROTEIN
Prion diseases are a group of fatal neurodegenerative disorders characterized by the accumulation of a misfolded form (PrP(Sc)) of the cellular prion protein (PrP(C)) in the brains of affected individuals. The conversion of PrP(C) to PrP(Sc) is thought to involve a change in protein conformation fro...
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Main Authors: | , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2009
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2741132/ https://ncbi.nlm.nih.gov/pubmed/19221431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2009-0980 |
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