E-cadherin involved in inactivation of WNT/β-catenin signalling in urothelial carcinoma and normal urothelial cells

Constitutive activation of WNT signalling through β-catenin, which leads to increased transcription of TCF/β-catenin target genes, is crucial in the development of many human tumour types including colorectal carcinoma and hepatoma. Its role in urothelial cancer (TCC) is unclear, since typical activ...

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Bibliographic Details
Main Authors: Thievessen, I, Seifert, H-H, Swiatkowski, S, Florl, A R, Schulz, W A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741126/
https://ncbi.nlm.nih.gov/pubmed/12799639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601031
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